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CSIC study provides new data on the innate immune system

A study by the Consejo Superior de Investigaciones Científicas (CSIC) provides new data on the complement system, a basic component of the immune system of the human being, he acts out uncontrolled, can cause diseases such as macular degeneration the second cause of blindness in older people.

The work, published in the latest issue of the journal Proceedings of the National Academy of Sciences USA, focuses on the AP C3 convertase, a complex enzyme composed of two proteins key to the complement system responds quickly and effectively, eliminating pathogenic micro-organism or substance which led to its activation. The results help to determine its potential as a therapeutic target in diseases caused by failures of the complement system.


A study by the Consejo Superior de Investigaciones Científicas (CSIC) provides new data on the complement system, a basic component of the immune system of the human being, he acts out uncontrolled, can cause diseases such as macular degeneration the second cause of blindness in older people.

The work, published in the latest issue of the journal Proceedings of the National Academy of Sciences USA, focuses on the AP C3 convertase, a complex enzyme composed of two proteins key to the complement system responds quickly and effectively, eliminating pathogenic micro-organism or substance which led to its activation. The results help to determine its potential as a therapeutic target in diseases caused by failures of the complement system.

Free e-books: Fluid flow studies in flexible tubes with internal flexible structures

Fluid flow through flexible tubes is of interest due to its dynamic similarity to that of fluid flow in veins, arteries, bronchial air ways, urethra, vocal codes peristaltic tubes, and flexible micro-fluidic devices. Similar behavior can be observed in diagnostic and therapeutic devices pressurized cuffs, prophylaxis, intra-aortic balloon counterpulsation, prosthetic heart devices, vein cannulation and prosthetic vocal codes. Due to the flexible material that constitutes the tube a state of total collapse is highly likely when the tube is subjected to excessive external forces. Thus, muscle contraction and expansion and external forces that act upon the vessel wall all serve to deform the flexible tube thereby affecting the fluid flow area and fluid flow behavior. It is reasonable to conclude that fluid flow within a flexible vessel is a function of the fluid properties, material prosperities of the flexible structures and any external forces. Furthermore within the flexible tube, the presence of attached internal structures can impose further limitations on the fluid flow. Such systems can be found in vein and valves, heart valves and also in nebulizers.


Fluid flow through flexible tubes is of interest due to its dynamic similarity to that of fluid flow in veins, arteries, bronchial air ways, urethra, vocal codes peristaltic tubes, and flexible micro-fluidic devices. Similar behavior can be observed in diagnostic and therapeutic devices pressurized cuffs, prophylaxis, intra-aortic balloon counterpulsation, prosthetic heart devices, vein cannulation and prosthetic vocal codes. Due to the flexible material that constitutes the tube a state of total collapse is highly likely when the tube is subjected to excessive external forces. Thus, muscle contraction and expansion and external forces that act upon the vessel wall all serve to deform the flexible tube thereby affecting the fluid flow area and fluid flow behavior. It is reasonable to conclude that fluid flow within a flexible vessel is a function of the fluid properties, material prosperities of the flexible structures and any external forces. Furthermore within the flexible tube, the presence of attached internal structures can impose further limitations on the fluid flow. Such systems can be found in vein and valves, heart valves and also in nebulizers.

Brantner & Associates, Inc.Engineer

SEA CON® Brantner & Associates, Inc., located in East County San Diego, is the leading manufacturer of underwater electrical and fiber optic connector assemblies for over 40 years. Over 400 dedicated employees work together throughout the world to serve military and offshore oil drilling industries. Currently, SEA CON® Brantner & Associates, Inc. has an opening for Electrical/Mechanical Engineer. We offer competitive compensation and a company paid employee benefits package which includes medical, dental, and life insurance. Join our term in a casual, friendly atmosphere.


SEA CON® Brantner & Associates, Inc., located in East County San Diego, is the leading manufacturer of underwater electrical and fiber optic connector assemblies for over 40 years. Over 400 dedicated employees work together throughout the world to serve military and offshore oil drilling industries. Currently, SEA CON® Brantner & Associates, Inc. has an opening for Electrical/Mechanical Engineer. We offer competitive compensation and a company paid employee benefits package which includes medical, dental, and life insurance. Join our term in a casual, friendly atmosphere.

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